The genetic etiology of hereditary breast cancer has not been fully elucidated.Although germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development of hereditary breast cancers, at least half of all breast cancer families are not linked to these genes.To identify a comprehensive spectrum of genetic factors for heredita
This article contains a revised version of the inscription from Perge containing a military decree of Anastasius I.The fragments of this inscription were unearthed in 1974 during excavations at Perge.The inscription was discovered in about 850 fragments in an area to the south of northern fountain on the southern slopes of the acropolis.Today these
Jill P Smith1, Sandra Ice Maker I Bingaman1, David T Mauger2, Harold H Harvey1, Laurence M Demers3, Ian S Zagon41Departments of Medicine, 2Public Health Sciences, 3Pathology, and 4Neurosciences and Anatomy, Pennsylvania State University, College of Medicine, Hershey Medical Center, Hershey, PA, USABackground: Advanced pancreatic cancer carries the
Abstract Background Statin intake is associated with muscular side effects, among which the unmasking of latent myopathies and of malignant hyperthermia (MH) susceptibility have been reported.These findings, together with experimental data in small animals, prompt speculation that statin therapy may compromise the performance of skeletal muscle dur